The M5 is closed heading southbound after a horror lorry crash left a woman seriously hurt.
Police say a lorry collided with a car on the motorway in Devon shortly before 6am.
The injrued woman was airlifted to Derriford Hospital in Plymouth while several people from the same car were taken to the Royal Devon and Exeter Hospital in Exeter.
The horror collision has left the southbound carriageway closed between Junction 28 at Cullompton and Junction 29 at Exeter.
Huge queues have been seen tailing back as far as Junction 27 with gridlocked traffic being diverted away from the motorway.
Devon and Cornwall police have urged motorists to use alternate routes where possible and warned of long delays into the afternoon.
Traffic service Inrix reported: “Stationary traffic due to all traffic being temporarily held and accident, a lorry and a car involved on M5 Southbound between J28 A373 Station Road (Cullompton / Service Area) and J29 A3015 Honiton Road (Exeter / Honiton).
“Cameras show all traffic is being held.”